Marianna Zahurak, M.S.
Ms.
Zahurak earned a B.A. in Biology from the University of Maryland
Baltimore County in 1983 and earned a Master of Science degree
in Biostatistics and Epidemiology from Georgetown University Medical
School in 1985. She has been a biostatistician for the Johns Hopkins
Oncology Center since 1987 and her primary focus is to provide
statistical support for the clinical and laboratory investigators
in the center. This includes study design, statistical analyses
and the interpretation of results. Ms. Zahurak is currently involved
in projects from the head and neck, breast
cancer, gastrointestinal and lymphoma SPORE grants.
She worked with Dr. Misop Han and Dr. Steven Piantadosi to develop
a nomogram for recurrence probability
following radical prostatectomy for localized prostate cancer and
is currently working to externally validate this nomogram.
Ms. Zahurak’s involvement in statistical research includes
microarray data analysis, phase I study design, specifically the
continual reassessment method, and phase II robust optimal designs
in the presence of extra-binomial variability. She collaborated
with Dr. Jeanne Kowalski in the development of the Hypothesis-Based
Analysis of Microarrays (HAM) and the Correlative
Analysis of Microarrays (CAM) methods. Currently she is working on several Agilent microarray
projects with the Oncology Bioinformatics group lead by Dr. Giovanni
Parmigiani and most recently submitted a paper describing pre-processing
methods for Agilent data.
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