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550 North Broadway, Suite 1103
Baltimore, Maryland 21205-2013
phone: (410) 955-4884
fax: (410) 955-0859

Active Areas of Research

Postdoctoral Positions Available - See Announcement

The following list represents a few of the areas of research with which our faculty are involved:

Early developmental trial designs: studies of the quantitative properties and design of translational clinical trials.

Dose finding clinical trials: implementation and use of the continual reassessment method for dose finding oncology studies.  Methods for general dose finding based on optimization of safety and benefit.

Design and conduct of randomized clinical trials: statistical methods for the design and analysis of multicenter trials in oncology, surgery, and neurologic disease.

Risk prediction modeling in hereditary cancer: models for identifying individuals at high risk of carrying disease-causing mutation of the BRCA genes (see also BRCAPRO) and the HNPCC genes.

Statistical methods for genomic analysis: models for the analysis of SAGE data, and for identification of novel cancer subtypes using molecular profiles.

Statistical models for medical decision making and chronic disease simulation models.

Bayesian simulation: multilevel Bayesian models; semiparametric Bayesian models.