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550 North Broadway, Suite 1103
Baltimore, Maryland 21205-2013
phone: (410) 955-4884
fax: (410) 955-0859

Mei-Fen Yeh, Sc.M.

Contact Information:
Department of Oncology Biostatistics
Johns Hopkins School of Medicine
Baltimore, Maryland 21205
W: 410.614.2338
F: 410.614.1328
mfyeh1@jhmi.edu

Mei-Fen Yeh received her B.S. in Pharmacy from National Taiwan University, M.P.H. from State University of New York at Albany, and Sc.M. from Biostatistics department from Johns Hopkins University Bloomberg School of Public Health.  Ms. Yeh is currently a biostatistician in the Biostatistics Division of the Department of Oncology.

Research Interests:

Mei-Fen Yeh's research interest is in the area of statistical genetics. With the continuous collaboration with her master thesis advisor, Dr. Kowalski, she develops and implements non-parametric methods for the analysis of high-dimensional gene sequence data, to examine the association between usage drugs abuse and viral sequence diversity within HIV-1 gene regions targeted by antiretroviral therapies.

Her other research interest is to develop distance-based statistical methods with an application in the proteomics area.

Software Development:

Gene_S: a menu-driven collection of S-plus functions created to facilitate two group analysis of gene region sequence pairs

Presentations:

Yeh, M.F., Kowalski, J., Zhang, G.W, Shao, Q., Templeton, A., Young, M., Gange, S., Schneider, S., Markham, R. (2004) A History of Injection Drug Use Among Women Is Associated with Increased Diversity in the HIV-1 Protease Gene. Invited poster, read poster as PDF, 11th Conference on Retroviruses and Opportunistic Infections, February 8-11, San Francisco, CA.

Yeh, M.F., Kowalski, J., Zhang, G.W, Shao, Q., Schneider, M., Templeton, A., Markham, R. (2004) Nonparametric Analysis of Sequence Heterogeneity Associated with Injection Drug Usage. Contributed poster, East North American Region Meeting of the International Biometric Society, March 28-31, Pittsburgh, PA.

Publications:

(In progress) Yeh, M.F., Kowalski, J., Markham, R., The Association between Injection Drug Use and Clonal HIV Genetic Diversity

(In progress) Yeh M.F., Kowalski, J., White, N., Zhang, Z., Comparative Methods on Protein Array Analysis of Many Samples with Very Few Replicates

Links:

Los Alamos Natl. Lab HIV Database: contains data on HIV genetic sequences, immunological epitopes, drug resistance-associated mutations, vaccine trials, and a large number of tools that can be used to analyze these data.

Protein Explorer: a free software for visualizing the three-dimensional structures of protein, DNA, and RNA macromolecules.